Monday, March 22
14:00-14:15 Welcome by Anita Marchfelder
Session 1 – Chair: Lennart Randau
14:15-14:30
(Hess) Raphael Bilger, Viktoria Reimann, Marcus Ziemann
„Regulation of CRISPR-Cas systems in Cyanobacteria“
14:35-14:50
(Wilde) Jin Ding
„Allosteric regulation of CRISPR type III-associated CARF domain proteins by cyclic
oligoadenylate signaling in Cyanobacteria“
14:55-15:10
(Sharma) Sahil Sharma
„Non-canonical crRNAs derived from host transcripts enable multiplexable RNA detection“
15:15-15:30
(Marchfelder) Pascal Märkle
„A small RNA is linking CRISPR-Cas and zinc transport“
15:35-15:50
(Beisel) Franziska Wimmer
„A novel TXTL-based PAM assay for probing the diversity and alternative functions of Type I CRISPR-Cas systems“
15:55-16:10 Break
Session 2 – Chair: Wolfgang Hess
16:10-16:25
(Grohmann) Elisabeth Wörle
„Decoupling the bridge helix of Cas12a results in a reduced trimming activity and impaired conformational transitions“
16:30-16:45
Sabine Schneider
„Structural and mechanistic insights into Cas13a from Rhodobacter capsulatus“
16:50-17:05
(Bange) Nils Mais
„Type I-Fv in action – a study of structure“
17:10-17:25
(Ziegler) Tina Wöhrmann
„CRISPR-Whisper“
17:30-17:45
(McHardy) Philipp Münch
„Identification of Natural CRISPR Systems and Targets in the Human Microbiome“
Tuesday, March 23
Session 3 – Chair: Chase Beisel
14:15-14:30
(Schoen) Denise Müller
„Deciphering the role of the CRISPR-Cas system in Neisseria meningitidis in host cell adhesion“
14:35-14:50
(Randau) Mariana Sanchez-Londono
„Characterization of anti-plasmid and CRISPRi activities of a Pseudomonas oleovorans Type IVA CRISPR-Cas system“
14:55-15:10
(Endesfelder) Bartosz Turkowyd
„In vivo single-molecule localization microscopy studies of CRISPR systems in Bacteria and Archaea“
15:15-15:30
Franz Baumdicker
„Evolutionary Dynamics of CRISPR“
15:35-15:50
(Seidel) Julene Madariaga Marcos
„Dissecting the target recognition by CRISPR-Cas effector complexes with novel single-molecule techniques“
15:55-16:10 Break
Session 4 – Chair: Dina Grohmann
16:10-16:25
(Backofen) Alexander Mitrofanov
„Towards better CRISPR loci identification: CRISPRidentify and CRISPRtracr“
16:30-16:45
(Schmitz-Streit) Finn Ole Petersen
„The Casposon of Methanosarcina mazei – Function and Evolution“
16:50-17:05
Björn Voß
„Improved characterisation of CRISPR-Cas systems by optimised metagenome assembly“
17:10-17:25
Henning Urlaub
„Protein-Nucleic Acid crosslinking – an update“
17:30-17:45
(Wohlleben) Ewa Musiol-Kroll
„Functional Analysis of CRISPR-Cas in Antibiotic-producing Actinomycetes“